Interesting to see that I have pretty much the same (apparently wonky) setup with my ZigBee coordinator plugged into my Home Assistant mini-PC (via extension cable) in the basement of my house.
Though I have a better supported adapter (from Slaesh) it is definitely not in the middle of the house. It works fine so far with about 100 devices and it seems the backbone is strong enough so the basement location is not a big problem. Still I wonder if the mesh could be improved by getting a network-enabled adapter and placing it somewhere more central.