I didn't say it wasn't worth enabling (FWIW I used lockdown mode in the past and now use GrapheneOS); just don't expect it to protect you from these kinds of threats. You might get lucky, but you can't rely on it (and it still might be worth it to you just based on that).
A big part of security is understanding what you're protecting against, and weighing the effect of increasing the security of your system on its usability.