Yup, my computers use full disk encryption and have long passwords (>15 characters). And those passwords are different from my login passwords. I find myself not shutting down as often because it's a pain to log back in.
So they're cost competitive with Google Titan. I would go with the Yubikey in this case since they have a stronger track record, but I also don't see much of a conflict of interest with Google (they don't want your logins, they just want your Internet data).