I have a lot of services. I use Ansible to manage many of them, so they're all in one VM. I use Home Assistant, which works best when installed as a whole VM or on bare metal. For the remaining services that I have yet to set up with Ansible, I keep the services that need the GPU on one VM, and everything else on another. Finally, I have an LXC container that is my SSH entrypoint and Ansible management system.
I could technically use TrueNAS Scale as a hypervisor for all this, but Proxmox has a lot of quality-of-life features that make it a better hypervisor. I could use Proxmox for ZFS and shares, but TrueNAS has has a lot of quality-of-life features that make it a much better NAS, so I virtualize it.