I use artix for my work and personal servers. There are a few kvm hosts and several virtual machines with internet facing services such as dns, web, mail, wireguard. On the way to be fully gitopsed with ansible.
Sometimes I borrow specific packages from arch repos but almost everything can be made with artix alone.
The only notable issue I had was with cloud-init which I replaced with more complex playbooks and bash scripts.
Ama