I definitely noticed, before quantum (like 5 years ago) single page apps and frameworks like react were becoming a thing, and it was noticeably less snappy than chrome
After they announced the rewrite to better handle shadow doms and partial repaints, I switched for everything but development
Since then, they've done another rewrite, and the dev tools are closer, so I only open chrome when a site I have to use isn't working, or by client request