If you know who I am and what I like, gimme some damn relevant ads. No, me clicking the "Not interested" button doesn't mean the next ad is the same damn thing. Worst are those when I search for something for several weeks, and when I finally find it and buy it a week later, I get peppered by the VERY THING for another week.
No offense, of course. The ad industry is just insanity for me.
For those "Just use an ad blocker" - I do, I just occasionally unblock sites to show support.